brain

Publications

In recent years, the Kasahara Lab has published research in a variety of academic journals, including Cancer Gene Therapy, Science Translational Medicine, and Neuro-Oncology. Below includes a selection of recent publications.

 

Replication-competent vectors and empty virus-like particles: new retroviral vector designs for cancer gene therapy or vaccines

Dalba C, Bellier B, Kasahara N, Klatzmann D.

Mol Ther. 2007 Mar 1; 15 (3): 457-66. doi: 10.1038/sj.mt.6300054. Epub 2007 Jan 23.
PubMed Link >

Tumor-selective gene expression in a hepatic metastasis model after locoregional delivery of a replication-competent retrovirus vector

Hiraoka K, Kimura T, Logg CR, Kasahara N.

Clin Cancer Res. 2006 Dec 1; 12 (23): 7108-16. doi: 10.1158/1078-0432.CCR-06-1452.
PubMed Link >

International Society for Cell and Gene Therapy of Cancer (ISCGT) annual meeting: conference overview and introduction to the symposium papers

Guinn BA, Norris JS, Huang L, Farzaneh F, Kasahara N, Deisseroth AB.

Cancer Immunol Immunother. 2006 Nov 1; 55 (11): 1406-11. doi: 10.1007/s00262-006-0187-x. Epub 2006 Jun 17.
PubMed Link >

L1 retrotransposition in nondividing and primary human somatic cells

Kubo S, Seleme MC, Soifer HS, Perez JL, Moran JV, Kazazian HH Jr, Kasahara N.

Proc Natl Acad Sci USA. 2006 May 23; 103 (21): 8036-41. doi: 10.1073/pnas.0601954103. Epub 2006 May 12.
PubMed Link >

Use of replication-competent retroviral vectors in an immunocompetent intracranial glioma model

Wang W, Tai CK, Kershaw AD, Solly SK, Klatzmann D, Kasahara N, Chen TC.

Neurosurg Focus. 2006 Apr 15; 20 (4): E25. doi: 10.3171/foc.2006.20.4.1.
PubMed Link >

Beyond oncolytic virotherapy: replication-competent retrovirus vectors for selective and stable transduction of tumors

Dalba C, Klatzmann D, Logg CR, Kasahara N.

Curr Gene Ther. 2005 Dec 1; 5 (6): 655-67. doi: 10.2174/156652305774964659.
PubMed Link >

Retargeting of adenoviral vector using basic fibroblast growth factor ligand for malignant glioma gene therapy

Wang W, Zhu NL, Chua J, Swenson S, Costa FK, Schmitmeier S, Sosnowski BA, Shichinohe T, Kasahara N, Chen TC.

J Neurosurg. 2005 Dec 1; 103 (6): 1058-66. doi: 10.3171/jns.2005.103.6.1058.
PubMed Link >

Single-shot, multicycle suicide gene therapy by replication-competent retrovirus vectors achieves long-term survival benefit in experimental glioma

Tai CK, Wang WJ, Chen TC, Kasahara N.

Mol Ther. 2005 Nov 1; 12 (5): 842-51. doi: 10.1016/j.ymthe.2005.03.017.
PubMed Link >

Development of packaging cell lines for generation of adeno-associated virus vectors by lentiviral gene transfer of trans-complementary components

Nakamura S, Nakamura R, Shibata K, Kobayashi M, Sahara N, Shigeno K, Shinjo K, Naito K, Ohnishi K, Kasahara N, Iwaki Y.

Eur J Haematol. 2004 Oct 1; 73 (4): 285-94. doi: 10.1111/j.1600-0609.2004.00290.x.
PubMed Link >

Intradermal injection of lentiviral vectors corrects regenerated human dystrophic epidermolysis bullosa skin tissue in vivo

Woodley DT, Keene DR, Atha T, Huang Y, Ram R, Kasahara N, Chen M.

Mol Ther. 2004 Aug 1; 10 (2): 318-26. doi: 10.1016/j.ymthe.2004.05.016.
PubMed Link >

Subunit-specific coordinate upregulation of sodium pump activity in alveolar epithelial cells by lentivirus-mediated gene transfer

Qiao R, Zhou B, Harboe-Schmidt E, Kasahara N, Kim KJ, Liebler JM, Crandall ED, Borok Z.

Hum Gene Ther. 2004 May 1; 15 (5): 457-68. doi: 10.1089/10430340460745784.
PubMed Link >

Identification and biochemical characterization of a Werner's syndrome protein complex with Ku70/80 and poly(ADP-ribose) polymerase-1

Li B, Navarro S, Kasahara N, Comai L.

J Biol Chem. 2004 Apr 2; 279 (14): 13659-67. doi: 10.1074/jbc.M311606200. Epub 2004 Jan 20.
PubMed Link >

Inhibition of orthotopic human bladder tumor growth by lentiviral gene transfer of endostatin

Kikuchi E, Menendez S, Ohori M, Cordon-Cardo C, Kasahara N, Bochner BH.

Clin Cancer Res. 2004 Mar 1; 10 (5): 1835-42. doi: 10.1158/1078-0432.ccr-03-0099.
PubMed Link >

Retrovirus-mediated gene transfer to tumors: utilizing the replicative power of viruses to achieve highly efficient tumor transduction in vivo

Logg CR, Kasahara N.

Methods Mol Biol. 2004 Jan 1; 246: 499-525. doi: 10.1385/1-59259-650-9:499.
PubMed Link >

Antibody-mediated targeting of replication-competent retroviral vectors

Tai CK, Logg CR, Park JM, Anderson WF, Press MF, Kasahara N.

Hum Gene Ther. 2003 May 20; 14 (8): 789-802. doi: 10.1089/104303403765255174.
PubMed Link >